Cape Girardeau Main Post Office

Post office

320 N Frederick St, Cape Girardeau, MO 63701

By appointment. Please call 573-335-3137.

Appointment required

Hours and addresses come from the State Department listing, updated November 2, 2026.

Book at USPS Directions Facilities in Cape Girardeau Facilities in Missouri

Cape Girardeau Main Post Office accepts new U.S. passport applications in person in Cape Girardeau, MO. First-time and child visits are booked on the USPS scheduler. Search ZIP 63701. How to apply · How to renew

Other facilities in Cape Girardeau

Cape Girardeau Public Library