Lake City Post Office

Post office

226 W Main St, Lake City, SC 29560

(843) 394-2421

Appointments are required.

Appointment required

Hours and addresses come from the State Department listing, updated November 2, 2026.

Book at USPS Directions Facilities in Lake City Facilities in South Carolina

Lake City Post Office accepts new U.S. passport applications in person in Lake City, SC. First-time and child visits are booked on the USPS scheduler. Search ZIP 29560. How to apply · How to renew